John-Stephen Taylor
Office Contact Information
Campus Box 1134
Research specialization
1975, Phi Beta Kappa, MIT
1976, Merck Index Award for Scholastic Excellence in Chemistry, MIT
1977, 1978, Teaching Award, Columbia University
1981, Pegram Award for Outstanding Graduate Work, Columbia University
1981 - 1983, Damon Runyon-Walter Winchell Cancer Fund Fellow
1988 - 1990, Alfred P. Sloan Foundation Fellow
1993 - 2001, NIH Merit Award
1993, American Chemical Society St. Louis Award
2005-2007, Special Recognition for Excellence in Mentoring, Washington University
Publications
Nucleic Acid Triggered Catalytic Drug Release, Zhaochun Ma, John-Stephen Taylor*, 2000 Proc. Natl. Acad. Sci. 97, 11159-63.
Cai, J., Li, X., Yue, X., Taylor*, J. S., Nucleic Acid Triggered Fluorescent Probe Activation by the Staudinger Reaction. 2004 J. Am. Chem. Soc., 126,16324-5.
Sun, X., Fang, H., Li, X., Rossin, R., Welch, M. J., Taylor*, J. S., MicroPET imaging of MCF-7 tumor in mice via unr mRNA-targeted peptide nucleic acids, 2005 Bioconjug. Chem. 16, 294-305
Vu, B., Cannistraro, V.J., Sun, L. and Taylor, J.S. DNA synthesis past a 5-methylC-containing cis-syn-cyclobutane pyrimidine dimer by yeast pol eta is highly nonmutagenic. 2006 Biochemistry, 45, 9327-35.
Su DG, Kao JL, Gross ML, & Taylor JS Structure determination of an interstrand-type cis-anti cyclobutane thymine dimer produced in high yield by UVB light in an oligodeoxynucleotide at acidic pH 2008 J. Am. Chem. Soc. 130, 11328-11337.
Fang, H., Zhang, K., Shen, G., Wooley, K.L. and Taylor, J.S. Cationic Shell-crosslinked Knedel-like (cSCK) Nanoparticles for Highly Efficient PNA Delivery. 2009 Molecular Pharmaceutics, in press.
Wang, R. E.; Kao, J. L.-F.; Hilliard, C. A.; Pandita, R. K.; Roti Roti, J. L.; Hunt, C. R.; Taylor, J.-S. Inhibition of Heat Shock Induction of Heat Shock Protein 70 and Enhancement of Heat Shock Protein 27 Phosphorylation by Quercetin Derivatives J. Med. Chem. 2009, in press
Courses Taught
Biology 181 Freshman Seminar in Biology
Chemistry 181 Freshman Seminar in Chemistry
Chemistry 251 Organic Chemistry I
Chemistry 252 Organic Chemistry II
Chemistry 257 Organic Chemistry Laboratory
Chemistry 358, Qualitative Organic Analysis Laboratory
Chemistry 453 Bioorganic Chemistry
Chemistry 458 Organic Mechanisms Journal Club
Chemistry 520, Nucleic Acids Chemistry
Biology 5318 DNA Repair
Biology 5432 DNA Structure and Function
Chemistry 558 Spectral Methods in Organic Chemistry
Biology 5911 Special Topics: Mutagenesis adn Repair