Multiple active site histidine protonation states in Acetobacter aceti N⁵-carboxyaminoimidazole ribonucleotide mutase (PurE) detected by REDOR NMR
J. Schaefer, H. Jiang, A. E. Ransome & T. J. Kappock, Biochemistry (2007) 46:9507-9512
Abstract «» Full text «» doi:10.1021/bi700899q

Cloning and transcriptional analysis of Crepis alpina fatty acid desaturases affecting the biosynthesis of crepenynic acid.
J.-W. Nam & T. J. Kappock, J. Exp. Bot. (2007) 58:1421-1432
Abstract «» Full text «» doi:10.1093/jxb/erm005

N⁵-CAIR mutase: Role of a CO₂ binding site and substrate movement in catalysis.
A. A. Hoskins, M. Morar, T. J. Kappock, I. I. Mathews, J. B. Zaugg, T. E. Barder, P. Peng, A. Okamoto, S. E. Ealick & J. Stubbe, Biochemistry (2007) 46:2842-2855.
Abstract «» Full text «» doi:10.1021/bi602436g

Atomic-resolution crystal structure of thioredoxin from the acidophilic bacterium Acetobacter aceti.
C. M. Starks, J. A. Francois, K. M. MacArthur, B. Z. Heard & T. J. Kappock, Protein Sci. (2007) 16:92-98
Abstract «» Full text «» doi:10.1110/ps.062519707

Alanine racemase from the acidophile Acetobacter aceti.
J. A. Francois & T. J. Kappock, Protein Expression Purif. (2007) 51:39-48
Abstract «» Full text «» doi:10.1016/j.pep.2006.05.016

Structure of a NADH-insensitive hexameric citrate synthase that resists acid inactivation
J. A. Francois, C. M. Starks, S. Sivanuntakorn, H. Jiang, A. E. Ransome, J.-W. Nam, C. Z. Constantine & T. J. Kappock, Biochemistry (2006) 45:13487-13499.
Abstract «» Full text «» doi:10.1021/bi061083k

Biochemical and structural studies of N⁵-carboxyaminoimidazole ribonucleotide mutase from the acidophilic bacterium Acetobacter aceti.
C. Z. Constantine, C. M. Starks, C. P. Mill, A. E. Ransome, S. J. Karpowicz, J. A. Francois, R. A. Goodman & T. J. Kappock, Biochemistry (2006) 45:8193-8208.
Abstract «» Full text «» doi:10.1021/bi060465n

Acidophilic adaptations in the structure of Acetobacter aceti N⁵-carboxyaminoimidazole ribonucleotide mutase (PurE).
E. C. Settembre, J. R. Chittuluru, C. P. Mill, T. J. Kappock & S. E. Ealick, Acta Crystallog. D Biol. Crystallog. (2004) 60:1753-1760.
Abstract «» Full text «» doi:10.1107/S090744490401858X

Altered pathway routing in a class of Salmonella enterica serovar Typhimurium mutants defective in aminoimidazole ribonucleotide synthetase.
J. L. Zilles, T. J. Kappock, J. Stubbe & D. M. Downs, J. Bacteriol. (2001) 183:2234-2240.
Abstract «» Full text «» doi:10.1128/JB.183.7.2234-2240.2001

Modular evolution of the purine biosynthetic pathway.
T. J. Kappock, S. E. Ealick & J. Stubbe, Curr. Op. Chem. Biology (2000) 4:567-572.
Abstract «» Full text «» doi:10.1016/S1367-5931(00)00133-2

Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway.
I. I. Mathews, T. J. Kappock, J. Stubbe & S. E. Ealick, Structure (1999) 7:1395-1406.
Abstract «» Full text «» doi:10.1016/S0969-2126(00)80029-5

X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 Å resolution.
C. Li, T. J. Kappock, J. Stubbe, T. M. Weaver & S. E. Ealick, Structure (1999) 7:1155-1166.
Abstract «» Full text «» doi:10.1016/S0969-2126(99)80182-8

Investigation of the ATP binding site of Escherichia coli aminoimidazole ribonucleotide synthetase using affinity labeling and site-directed mutagenesis.
E. J. Mueller, S. Oh, E. Kavalerchik, T. J. Kappock, E. Meyer, C. Li, S. E. Ealick & J. Stubbe, Biochemistry (1999) 38:9831-9839.
Abstract «» Full text «» doi:10.1021/bi990638r

Evidence for the direct transfer of the carboxylate of N⁵-carboxyaminoimidazole ribonucleotide (N⁵-CAIR) to generate 4-carboxy-5-aminoimidazole ribonucleotide catalyzed by Escherichia coli PurE, an N⁵-CAIR mutase.
E. Meyer, T. J. Kappock, C. Osuji & J. Stubbe, Biochemistry (1999) 38:3012-3018.
Abstract «» Full text «» doi:10.1021/bi9827159

Kinetic and structural investigations of channeling in the purine biosynthetic pathway.
T. J. Kappock, A. Qiao, J. Stubbe, W. Wang & S. E. Ealick (1998) in Enzymatic Mechanisms, PA Frey and DB Northrop, Eds., IOS Press, Amsterdam, 139-149.

X-ray crystal structure of glycinamide ribonucleotide synthetase from Escherichia coli.
W. Wang, T. J. Kappock, J. Stubbe & S. E. Ealick, Biochemistry (1998) 37:15647-15662. 
Abstract «» Full text «» doi:10.1021/bi981405n

Spectroscopic characterization of the catalytically competent ferrous site of the resting, activated, and substrate-bound forms of phenylalanine hydroxylase.
K. E. Loeb, T. E. Westre, T. J. Kappock, N. Mitic, E. Glasfeld, J. P. Caradonna, B. Hedman, K. O. Hodgson & E. I. Solomon, J. Am. Chem. Soc. (1997) 119:1901-1915. 
Abstract «» Full text «» doi:10.1021/ja962269h

Pterin-dependent amino acid hydroxylases.
T. J. Kappock & J. P. Caradonna, Chem. Rev. (1996) 96:2659-2756.
Full text «» doi:10.1021/cr9402034

Spectroscopic and kinetic properties of unphosphorylated rat hepatic phenylalanine hydroxylase expressed in Escherichia coli. Comparison of resting and activated states.
T. J. Kappock, P. C. Harkins, S. Friedenberg & J. P. Caradonna, J. Biol. Chem. (1995) 270:30532-30544.
Abstract «» Full text «» doi:

Solubilization, cellular uptake, and activity of beta-carotene and other carotenoids as inhibitors of neoplastic transformation in cultured cells.
R. V. Cooney, T. J. Kappock, A. Pung & J. S. Bertram, Methods Enzymol. (1993) 214:55-68. 

Diverse carotenoids protect against chemically-induced neoplastic transformation.
J. S. Bertram, A. Pung, M. Churley, T. J. Kappock, L. R. Wilkins & R. V. Cooney, Carcinogenesis (1991) 12:671-678.